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  On disease and healing: a theoretical sketch

Mannone, M., Fazio, P., Ribino, P., Marwan, N. (2024): On disease and healing: a theoretical sketch. - Frontiers in Applied Mathematics and Statistics, 10, 1468556.
https://doi.org/10.3389/fams.2024.1468556

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Mannone, Maria1, Autor              
Fazio, Peppino2, Autor
Ribino, Patrizia2, Autor
Marwan, Norbert1, Autor              
Affiliations:
1Potsdam Institute for Climate Impact Research, ou_persistent13              
2External Organizations, ou_persistent22              

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 Zusammenfassung: The onset and progression of a neurological disease can often be explained in terms of brain-network alteration. They can be formalized as the action of an operator representing the disease, the so-called K-operator, acting on the network. The healing process can thus be seen as the inverse of the disease mechanism. However, perfect healing is often impossible to achieve. Here, we formalize the ideal healing in terms of perturbative variation of the possible partial healing. The modeling and analytical strategy is based on techniques from theoretical physics, with the language of matrix operators. In addition, using the language of category theory, we also formalize the progressive abstraction from the reality of diseased patients to the definition of a disease and the comparison between different diseases as a natural transformation between colimits. This theoretical presentation can provide a new, interdisciplinary perspective on neurological investigation and possibly foster new theoretical-experimental developments.

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Sprache(n): eng - Englisch
 Datum: 2024-09-192024-09-19
 Publikationsstatus: Final veröffentlicht
 Seiten: 8
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.3389/fams.2024.1468556
MDB-ID: No data to archive
PIKDOMAIN: RD4 - Complexity Science
Organisational keyword: RD4 - Complexity Science
Working Group: Development of advanced time series analysis techniques
Research topic keyword: Nonlinear Dynamics
Research topic keyword: Complex Networks
Model / method: Nonlinear Data Analysis
Research topic keyword: Health
Model / method: Quantitative Methods
Model / method: Qualitative Methods
OATYPE: Gold Open Access
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Titel: Frontiers in Applied Mathematics and Statistics
Genre der Quelle: Zeitschrift, Scopus, oa
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 10 Artikelnummer: 1468556 Start- / Endseite: - Identifikator: CoNE: https://publications.pik-potsdam.de/cone/journals/resource/frontiers-applied-mathematics_statistics
Publisher: Frontiers