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  Integrating Planetary Health in Health Guidelines (GRADE Guidance 46)

Piggott, T., Saadat, P., Herrmann, A., Tetelbom Stein, A., Darzi, A. J., Haines, A., Bognanni, A., Sousa-Pinto, B., Michels, C., Akl, E. A., Poluzzi, E., Senerth, E., Madrid, E., Barbic, F., de’Donato, F., Nonino, F., Vist, G. E., Neumann, I., Bracchiglione, J., Bousquet, J., Meerpohl, J. J., Antó, J. M., Scahill, K. A., Qiu, K., Miersch, K., Saif-Ur-Rahman, K., Vasanthan Thinagaran, L., Benton, L., Schwingshackl, L., Siedler, M. R., Bala, M. M., Metzendorf, M.-I., Aloosh, M., Cinquini, M., Cumpston, M., Skoetz, N., Oloyede, O., Alonso-Coello, P., Dahm, P., Wang, Q., Vieira, R. J., Morgan, R. L., Murthy, S., Hofstede, S., Laot-Cabon, S., Thomander, T., Siebert, U., Leontiadis, G. I., Schünemann, H. (2026): Integrating Planetary Health in Health Guidelines (GRADE Guidance 46). - Annals of Internal Medicine, 179, 6, 874-884.
https://doi.org/10.7326/ANNALS-25-04761

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 Creators:
Piggott, Thomas1, Author
Saadat, Pakeezah1, Author
Herrmann, Alina1, Author
Tetelbom Stein, Airton1, Author
Darzi, Andrea J.1, Author
Haines, Andy1, Author
Bognanni, Antonio1, Author
Sousa-Pinto, Bernardo1, Author
Michels, Charlotte1, Author
Akl, Elie A.1, Author
Poluzzi, Elisabetta1, Author
Senerth, Emily1, Author
Madrid, Eva1, Author
Barbic, Franca1, Author
de’Donato, Francesca1, Author
Nonino, Francesco1, Author
Vist, Gunn Elisabeth1, Author
Neumann, Ignacio1, Author
Bracchiglione, Javier1, Author
Bousquet, Jean1, Author
Meerpohl, Joerg J.1, AuthorAntó, Josep M.1, AuthorScahill, Karolina A.1, AuthorQiu, Kavin1, AuthorMiersch, Klaas1, AuthorSaif-Ur-Rahman, KM1, AuthorVasanthan Thinagaran, Lenny1, AuthorBenton, Lorna1, AuthorSchwingshackl, Lukas1, AuthorSiedler, Madelin R.1, AuthorBala, Malgorzata M.1, AuthorMetzendorf, Maria-Inti2, Author           Aloosh, Mehdi1, AuthorCinquini, Michela1, AuthorCumpston, Miranda1, AuthorSkoetz, Nicole1, AuthorOloyede, Oyekola1, AuthorAlonso-Coello, Pablo1, AuthorDahm, Philipp1, AuthorWang, Qi1, AuthorVieira, Rafael José1, AuthorMorgan, Rebecca L.1, AuthorMurthy, Srinivas1, AuthorHofstede, Stefanie1, AuthorLaot-Cabon, Sylvie1, AuthorThomander, Tuuli1, AuthorSiebert, Uwe1, AuthorLeontiadis, Grigorios I.1, AuthorSchünemann, Holger1, Author more..
Affiliations:
1External Organizations, ou_persistent22              
2Potsdam Institute for Climate Impact Research, Potsdam, ou_persistent13              

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Free keywords: Child health; Climate change; GRading of Recommendations Assessment Development and Evaluation; Guidelines; Heath statistics; Hospital medicine; Prevention, policy, and public health; Preventive medicine; Rehabilitation medicine; Treatment guidelines
 Abstract: Human health and natural systems are intrinsically linked—stable natural systems enable healthy human life. Health systems aim to promote, restore, and maintain health. Health systems may promote human health while having detrimental effects on natural systems, contributing to the transgression of planetary boundaries, such as biosphere integrity, climate change, and the introduction of new entities like microplastics. To date, the health guideline field lacks methods to assess the impacts of health interventions on planetary boundaries. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group established the Planetary Health Project Group in 2023 to develop formal GRADE guidance for integrating planetary health into guideline recommendations to address this gap.
Guided by the concepts of planetary health and planetary boundaries and following established methods for GRADE guidance development, the project group conducted iterative case study analyses, expert workshops, and a 2-round global Delphi consensus process. Four case studies were selected for application of this guidance before recommendations were finalized. The GRADE Working Group approved the official guidance.
The Planetary Health Project Group presents 7 domains of guidance for incorporating planetary health aspects into the guideline development process, including highly desirable items and optional items. Highly desirable items include formally addressing planetary health in public health and health system guidelines and explicitly justifying its exclusion where it is not addressed. Judgments within the evidence-to-decision (EtD) framework should systematically integrate included evidence across the prioritized planetary boundaries and equity. This guidance aims to support guideline developers and policymakers in making evidence-based, trustworthy recommendations to protect individual and planetary health, while maintaining thoroughness and feasibility for guideline developers within the GRADE approach.

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Language(s): eng - English
 Dates: 2026-05-122026-06-16
 Publication Status: Finally published
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.7326/ANNALS-25-04761
PIKDOMAIN: RD5 - Climate Economics and Policy - MCC Berlin
Organisational keyword: RD5 - Climate Economics and Policy - MCC Berlin
Working Group: Evidence for Climate Solutions
Research topic keyword: Planetary Boundaries
Research topic keyword: Health
MDB-ID: No data to archive
 Degree: -

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Title: Annals of Internal Medicine
Source Genre: Journal
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Publ. Info: -
Pages: - Volume / Issue: 179 (6) Sequence Number: - Start / End Page: 874 - 884 Identifier: CoNE: https://publications.pik-potsdam.de/cone/journals/resource/1539-3704
Publisher: American College of Physicians